The sequence downstream of the translation initiation codon was replaced with a cassette containing cre/ERT2 (ESR1), IRES, lacZ gene with a nuclear localization signal, and neo gene. The absence of transcript expression was confirmed by in situ hydridization on cervical spinal cord sections of P0 mice. (J:149553)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count