A floxed neo cassette was inserted upstream of exon 16 (formerly 15) and an additional loxP site was inserted downstream of exon 16. Cre mediated recombination removed the neo cassette leaving exon 16 floxed. (J:149225)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count