A floxed neomycin cassette was placed upstream of the ATG-containing second exon with a third loxP site placed downstream of the exon. Homozygous mice were phenotypically normal suggesting the knocked in DNA had little effect on gene function. (J:149149)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count