An IRES-lacZ/neo cassette replaced most of exon 2, and all of exons 3-5 as well as the intervening intronic sequences. Gene inactivation was confirmed by a lack of signal in immunoblot analysis of cortical neuron lysates. (J:148903)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count