A loxP site was inserted into the BsaHI site in intron 1, and a loxP site and a FRT-flanked neomycin cassette was inserted into the XcmI site in intron 6. Mice carrying this allele were crossed with cre deleter mice to remove exons 2-6. Gene inactivation was confirmed by RT-PCR analysis of homozygous kidney extracts. (J:148648)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count