A loxP site and frt flanked neo cassette were inserted into intron 5 and a single loxP site was inserted into intron 8 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exons 6 - 8 floxed. (J:148641)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count