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This transgene expresses the human STAT6 gene, with codons V625 and T626 mutated to express alanine and a C-terminal FLAG tag added, under transcriptional control of the CD2 locus control region. This promoter restricted expression of the transgene primarily to B and T lymphocytes. In addition to line 78, founder line 24 was also established. (J:133480)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
