LoxP sites were inserted upstream of exon 5 and downstream of exon 6. Protein expression was unaffected as determined by immunoblot analysis of embryonic fibroblasts. Cre-mediated recombination removed the drug selection cassette. (J:148391)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count