This transgene contains the coding sequence for a chimeric peptide consisting of the alpha subunit of ivermectin-sensitive C. elegans glutamate-gated choride channels (glc-1) and enhanced green fluorescent protein (EGFP) /icre), followed by a polyadenylation signal, an IRES and the cre recombinase gene, inserted into the mouse genomic bacterial artificial chromosome (BAC) RP23-283B12 at the ATG transcription initiation codon of the protein kinase C, delta (Prkcd) gene so that expression of the reporter and recombinase genes is driven by the regulatory sequences of the mouse gene. The GENSAT modified bacterial artificial chromosome (BAC) BX816 was used to generate this transgenic line. (J:100256)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/NTac
--
Insertion
--
--
--
20

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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