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A loxP site was inserted downstream of exon 6, and exons 7 through 11 were replaced with the corresponding cDNA and an frt flanked neo cassette with a 3' loxP site followed by an GFP gene. Germ line, flp mediated recombination remove the neo cassette. Expression of the EGFP gene can only be achieved through cre mediated removal of the cDNA encoding exons 7 through 11. (J:147946)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
