A loxP site was inserted upstream of exon 11 and a floxed neo cassette was inserted downstream of exon 18. Transient cre expression in ES cells removed the floxed neo cassette. (J:147820)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count