Log In|Sign Up
EN
The promoter, enhancer 1, exon 1, first intron/enchancer 2, and first 16 base pairs of exon 2 were used to drive muscle-specific expression of a dominant-negative human gene with nucleotide substitutions that result in the amino acid substitution of arginine for lysine at position 1003 (K1003R). Five lines were created with around 12 copies of the transgene. No line names were given. (J:71205)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
