Exons 14 to 17 were flanked by loxP sites and an frt flanked GK-neo selection cassette was inserted in a 3' position. The neomycin selection cassette was subsequently excised using an unspecified Actin-FLPe construct. (J:147611, J:225403)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count