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Exons 2 and 3 were replaced with a neomycin resistance cassette. Immunohistochemistry failed to detect protein in the brown adipose tissue, pancreas, liver or stomach of homozygote mice. Expression of the nearby Rpgrip1l gene (Ftm) is unaffected as determined by RT-PCR of hypothalamus, liver, and adipose tissue. (J:147471)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
