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A construct containing a 32-kb BST11071 restriction fragment including the human gene with 7 kb of upstream and 11 kb of downstream sequence, and containing the human functional upstream promoter polymorphism, -463GA (G allele) was used to create transgenic mice. This polymorphism is contained within a conserved sequence recognized by various nuclear receptors. Only one founder mouse was obtained. (J:130052)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
