A construct with the human skeletal alpha actin promoter driving the mouse calpain 3 sequence lacking exon 6, thereby removing the IS1 domain, was microinjected into (C57BL/6J x BALB/c)F2 oocytes and integrated via random insertion. (J:77348)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count