Exons 10 and 11 were replaced with a floxed promoter trap containing an splice acceptor, IRES, beta-geo cassette, and polyadenylation signal. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast lysates. (J:145116)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count