Atf6^tm1Kamo

Exons 8 and 9 were replaced with a floxed promoter trap containing an splice acceptor, IRES, beta-geo cassette, and polyadenylation signal. These exons code for the entire basic leucine zipper and most of the transmembrane domain. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast lysates. (J:145116)