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Exons 14 and 15 were replaced with a PGK neomycin selection cassette. The PGK neo cassette is spliced out during mRNA production and exon 13 is fused to exon 16 in the resulting mRNA. An additional six amino acids are added downstream of transmembrane domane 7. Expression of the mutant mRNA was confirmed by quantitative RT-PCR. (J:146953)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
