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This transgene comprises a full length cDNA encoding C-terminal polyhistidine-tagged mouse ADAM3 [a disintegrin and metallopeptidase domain 3 (cyritestin)] followed by a bovine globin polyadenylation signal and expressed under control of the testis specific promoter of the mouse calmegin gene. Western blot analysis demonstrated the presence of ADAM3 in both testis and sperm of homozygous Adam3tm1Ihig mice bearing this transgene. (J:147330)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
