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The mouse promoter was used to drive cardiac-specific expression of a human cDNA truncated at amino acid 448 and fused in frame via a collagen linker to lacZ. This truncation and fusion produces a constitutively active form. Two lines (30 and 32) were created. Line 32 has 6 copies of the transgene. (J:146424)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
