A loxP site was inserted upstream of exon 2 and a FRT-flanked neomycin resistance cassette with a downstream loxP site was inserted into intron 6. Correct targeting was confirmed by genomic PCR. (J:146583)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count