A cassette containing a bcl2 splice acceptor (SA) and a FRT-flanked beta-geo gene was inserted into the PvuII site upstream of exon 2. A loxP site was included upstream of the cassette and another loxP site was inserted into the BglII site in intron 3. Gene transcription is interrupted by the strong splice acceptor and terminated by a polyA sequence in the beta-geo gene. (J:146233, J:189192)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
Insertion
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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