A floxed neo cassette in inverse orientation was inserted into intron 1 and a loxP site was inserted into intron 3 via homologous recombination. The neo cassette was later removed leaving exons 2 and 3 floxed. (J:146078)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count