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A loxP site was inserted in exon 1 just in front of the ATG start site and a floxed neo cassette and cDNA containing a mutant form of Lrp5 with a flag tag were inserted in intron 1. The cDNA included 2 mutations 5 glycine and 171 valine. The neo cassette was later removed by Cre mediated recombination. (J:146078)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
