Using RMCE with transient cre recombinase expression, the neo cassette of Ednratm1Hku was replaced with a floxed cassette containing a lacZ gene and an frt-flanked puromycin resistance cassette. Expression of the lacZ gene was confirmed by beta-galactosidase assay. (J:131382)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count