The gene trap vector, which contains a beta-geo cassette, was inserted into intron 4. This allele also contains a 531 bp insertion derived by duplication from chromosome 16 at the junction between the vector and intron 4. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:142875)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count