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The human promoter was used to drive ubiquitous expression of the mouse gene with a silent point mutation at position 1077 (c.1077C->G) that forms a restriction enzyme site and allows for the insertion of 39 nucleotides. This produces a duplication of amino acids 353 to 365. Four lines were produced (C, D, E, and F) with line D selected as the representative line. (J:104378)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
