A floxed neo cassette was inserted upstream of exon 4 and a loxP site was inserted downstream of exon 10. Transient cre mediated recombination in ES cells removed the neo cassette leaving exons 4 through 10 floxed. (J:152528)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count