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2.5 Kb of the Cdh5 promoter was fused to a cre recombinase gene and placed between two genomic insulators derived from the chicken gamma-globulin gene. When crossed with cre-reporter strains, cre expression was detected in the yolk sac and vasculature of E9.5-E10.5 conceptus, and in the liver of E15.5 fetuses. Nearly all adult blood cells from mice carrying this transgene are derived from progentiors that have expressed cre. (J:145700)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
