An frt flanked neomycin selection cassette and a loxP site were inserted in intron 1. An additional loxP site was placed in intron 3. Excision of exons 2 and 3 will cause translation termination in exon 4. NF155 function will be ablated without affecting NF186. (J:145846)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count