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EN
LoxP sequences were inserted into a unique Pac1 site located 5' of exons 10 and 11. The human ERBB3 cDNA was ligated in frame into exon 12 using a Bcll site. The targeting vector also contained a neomycin-resistance cassette flanked by loxP sites and exon 17 and downstream sequences. The neomycin-resistance cassette was removed by Cre-recombination in ES cells. (J:207470)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
