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The human SFTPC promoter was used to drive lung-specific expression of a flag-tagged human fusion generated in human non-small-cell lung cancer due to recurrent chromosome inversion, inv(2)(p21p23). Two lines were created (502-4 and 501-3) that exhibit identical tumor-forming activity. Line 502-4 was selected as the representative line. Line 502-4 carried 30 copies of the transgene. (J:142679)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
