Hbb-y^tm2.1Fier

1.1 kb of DNA containing the promoter region, exon1, and exon2 was replaced with a floxed PGK-hygro selection cassette in ES cells already containing the targeted allele Hbb-bh1 allele. The selection cassettes in the two genes were subsequently excised by breeding mice to CMV-cre transgenic mice. This allele is only found in conjunction with Hbb-bh1. (J:145362)