An inducible cre cassette consisting of mammalian optimized cre fused to the human progesterone receptor followed by a neo selection cassette in the inverse orientation were inserted into the translation initiation site via homologous recombination. Following RU-496 treatment no Cre activity was detected in brain slices. (J:145152)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count