Pold1 mice were crossed to transgenic mice expressing Tg(Sycp1-cre)1Uchi. Germline expression of cre results in excision of the SV40 splice/polyadenylation signal and neomycin resistance cassette. The resulting allele codes for protein in which 3'-5' exonuclease activity is deficient. (J:144992)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Targeted
Insertion
--
1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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