A loxP site was inserted between exons 18 and 19 and a 1.8kb DNA fragment containing another loxP site as well as an frt flanked PGK-neomycin selection cassette was inserted between exons 20 and 21. Mice were crossed to Tg(EIF1A-flp)66Mim to remove the neomycin selection cassette. Exons 19 and 20 remain flanked by loxP sites. (J:144994)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count