A loxP site was inserted between exons 18 and 19 and a 1.8kb DNA fragment containing another loxP site as well as an frt flanked PGK-neomycin selection cassette was inserted between exons 20 and 21. Mice were crossed to Tg(EIF1A-flp)66Mim to remove the neomycin selection cassette. Exons 19 and 20 remain flanked by loxP sites. (J:144994)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
Insertion
--
1
8
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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