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Two PAC clones containing the human renin gene were used to generate transgenic mice. The clones were obrained from Genome Systems (PAC-28-13A and PAC-111-11L). Three lines were tested from each. The initial report emphasized 6407/1 and 6680/2, both of which displayed moderate renin expression. Line 6407/1 has been chosen as representative. (J:58897)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
