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This transgene consists of the mouse Amhr2 promoter driving expression of a constitutively active form of mouse Pik3ca and, following an IRES, GFP. The constitutively active form of Pik3ca was created by the addition of the avian src myristoylation sequence (MGSSKSKPK) to the N terminus of Pik3ca. Twelve founders were generated. This record represents pooled data from multiple founder lines. (J:144834)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
