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A cassette containing lacZ and neomycin genes replaced all 4 exons of the gene locus. Gene inactivation was confirmed by failure to detect the protein product in sera of homozygous mice whereas it was readily detectable in the sera of wild-type mice. (J:144927)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
