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A DNA fragment was replaced by a construct consisting of a splice acceptor, a floxed PGK-neo stop cassette, a mouse genomic DNA encoding Kcnj11 with a V59M mutation, and an frt flanked IRES GFP cassette via homologous recombination. Cre mediated removal of the floxed stop cassette allows for expression of Kcnj11. (J:144715)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
