A loxP site was inserted upstream of exon 3, and exons 5 through 6 were replaced with a cDNA encoding exons 5 through 14 followed by a human GH polyadenylation sequence, an HPRT minigene and loxP site. Exons 10 through 14 are duplicated in the gene but not the transcript. (J:144572)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Duplication, Insertion, Intragenic deletion
--
1
6
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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