Male mice carrying the Bag3tm1Jhl allele, which has exon 4 of the gene locus flanked by loxP sites, were bred with cre transgenic mice to excise exon 4 from the germline. Gene inactivation was confirmed in tail and liver extracts by failure to detect protein in immunoblot assays using three different antibodies raised against whole, COOH-terminal, and NH2-terminal peptides. (J:144416)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count