Tlr6^m4Btlr

This mutation was discovered in a TLR Signaling Screen of G3 progeny of an ENU mutagenized male mouse. The mutation comprises a T to C transition at nucleotide position 1454 of the gene (Genbank: NM_011604) that results in replacement of isoleucine by threonine at amino acid position 441 of the protein (I441T). (J:144168)