A beta-geo gene trap vector was inserted into exon 27 of the locus where the nucleophilic cysteine residue necessary for enzymatic activity is encoded. The gene trap vector inserted into the same location as the Ptpn3Gt(RRS555)Byg allele. No protein (endogenous or N-terminal portion of endogenous protein fused to beta-geo) was detected by immunoblot assays on homozygote brain extract. (J:144280)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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