A loxP site was inserted into intron 1 and a floxed and frt-flanked neo cassette was inserted into intron 3. Germ line, cre-mediated recombination was used to remove the neo cassette leaving exons 2 and 3 floxed. (J:143035)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count