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An Frt flanked PGK-neomycin cassette with a 3' loxP site was inserted in intron 2. A second loxP site was inserted 3' to exon 3. These mice were crossed to mice carrying Tg(ACTB-cre)2Mrt in order to excise exon 3. Mice resulting from this cross express a truncated message. Presence or absence of the PGK neo cassette has no affect on phenotype. (J:88784)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
