A cre/ERT2 cassette was inserted, along with an Frt flanked PGK-neomycin selection cassette, into the EcoRI site in exon 2 66 bp upstream of the translation initiation site. Heterozygous mice were later crossed with Tg(ACTFLPe)9205Dym mice to excise the neomycin selection cassette. (J:144088)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
2
91

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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