The rat Cyp1a1 promoter was used to drive the expression of a cre/ERT fusion that is inducible and dose-dependent. Cre expression in various tissues (small intestine, liver, bladder, stomach, esophagus, and gall bladder) is only achieved following treatment with tamoxifen and beta-naphthoflavone. Two lines were created with identical expression patterns. (J:143936)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count