Log In|Sign Up
EN
The modified chicken beta-actin promoter (CAG) was used to drive ubiquitous expression of a floxed lacZ gene with a nuclear localization signal and a triple polyadenylation sequence. The floxed cassette is followed by a constitutively active human BMPR1A sequence with the amino acid substitution of aspartic acid for glutamine at position 227 (Q227D), an IRES sequence, and the EGFP coding sequence. Expression of the constitutively active BMPR1A and EGFP are cre-dependent. No line information is available. (J:143588)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
